Anasys Instruments Corp. has licensed a Department of Energy Oak Ridge National Laboratory technology that allows for simultaneous chemical and physical characterization and could lead to advances in materials and drug development. The technique, which combines the power of atomic force microscopy and mass spectrometry, fills a void and streamlines analytical processes that are vital to science and industry, said Roshan Shetty, chief executive officer of Anasys Instruments. He also noted that the technology improves the current spatial resolution of ambient methods for mass spectrometry imaging by a factor of more than 100, resulting in imaging resolution as small as 250 nanometers, or 1/400th the thickness of a human hair. “This capability could have a tremendous impact on a broad field of applications in materials and life sciences ranging from single-cell imaging to polymer composites,” Shetty said. The license is the culmination of several years of research by a team led by Gary Van Berkel of ORNL’s Chemical Sciences Division. The team’s research has focused on mass spectrometry-based imaging pushing toward nanoscale imaging at ambient conditions using atomic force microscopy. “No other group has these capabilities, and this research distinction made Oak Ridge National Laboratory the ideal partner,” Shetty said.
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