Research from University of Leicester sniffs-out smell of disease in faeces Issued by University of Leicester Press Office on 1 September 2014 Images of the research team and of C-diff available to download at:https://www.dropbox.com/sh/4chms0mj7whb0ha/AAC8PDy2Vgi3K9d_XhtJ_zjua A fast-sensitive “electronic-nose” for sniffing the highly infectious bacteria C-diff, that causes diarrhoea, temperature and stomach cramps, has been developed by a team at the University of Leicester. An image of Clostridium difficile or C-diff. Credit: University of Leicester Using a mass spectrometer, the research team has demonstrated that it is possible to identify the unique ‘smell’ of C-diff which would lead to rapid diagnosis of the condition. What is more, the Leicester team say it could be possible to identify different strains of the disease simply from their smell – a chemical fingerprint – helping medics to target the particular condition. The research is published on-line in the journal Metabolomics. Professor Paul Monks, from the Department of Chemistry, said: “The rapid detection and identification of the bug Clostridium difficile (often known as C-diff) is a primary concern in healthcare facilities. Rapid and accurate diagnoses are important to reduce Clostridum difficileinfections, as well as to provide the right treatment to infected patients. “Delayed treatment and inappropriate antibiotics not only cause high morbidity
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