Tuesday 8 April 2014

Catheter innovation destroys dangerous biofilms

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An artistic configuration of catheters in various stages of being clogged by biofilm. Credit: Duke University For the millions of people forced to rely on a plastic tube to eliminate their urine, developing an infection is nearly a 100 percent guarantee after just four weeks. But with the help of a little bubble-blowing, biomedical engineers hope to bring relief to urethras everywhere. About half of the time, the interior of long-term urinary catheters become plagued by biofilms—structures formed by colonies of bacteria that are extremely difficult to kill. Once established, it is only a matter of time before the biofilm becomes a welcoming host for other, more dangerous bacteria or begins to choke urine drainage, causing leakage—or even trauma to the patient’s body. Duke University engineers have developed a new urinary catheter design that can eliminate nearly all of the hard-to-kill biofilm from the catheter’s walls. Instead of focusing on expensive antibacterial coatings, the researchers use physical deformation to knock the infectious film from its moorings. “A biofilm is like a city that protects and harbors harmful bacteria,” said Vrad Levering, a PhD student in biomedical engineering. “Our solution is like an earthquake that demolishes the infrastructure, leaving the rubble to be easily washed

The post Catheter innovation destroys dangerous biofilms has been published on Technology Org.


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